Lifesciences, Biomedical & Health Tech Solutions
At Nanosystems JP Inc., we utilize advanced silicon and semiconductor fabrication technologies to develop a diverse range of biochips and biomedical devices suitable for both in vivo and in vitro applications.
We offer comprehensive bio-fabrication prototyping and manufacturing services, ensuring the delivery of high-quality, innovative solutions to meet the evolving needs of the biomedical sector.
Drug Discovery
Organ-on-Chip (OoCs)
Organ-on-Chip (OoCs) technology replicates human organ functions on a microfluidic chip, enabling advanced drug discovery and testing. Different chip platforms can simulate various organs, including the brain (Brain-on-Chip), lungs (Lungs-on-Chip), liver, kidney, and heart. The fabrication of these biochips relies on advanced micro- and nano-fabrication techniques.
Micro-Electrode Array(MEA) for Neuroscience
Micro-Electrode Arrays (MEA) measure both extracellular and intracellular electrical activity and can also provide stimulation for cell excitation. These arrays have applications in drug development and food safety testing. MEAs can be designed for both in vitro and in vivo use.
For in vivo applications, microneedle-based electrodes can be implanted in the brain, enabling Brain-Computer Interfaces (BCI). We also fabricate polymer-based flexible electrocorticography (ECoG) electrode arrays. The general choice of material for in vitro arrays is glass, while in vivo microneedles are fabricated on silicon using deep etching or wet etching techniques.
Cell sorters
Diaphoresis-based cell sorter can be fabricated on the glass using transparent electrodes like ITO.
Micro and nano sieves can be fabricated using Si tech to separate the cells.
Cell culture chips
Nano or micro-structured cell culture chips allows superior cell growth.
Customizable glass array (Blind Glass Via) for single-cell experiments.
Biosensors for early disease diagnosis
The combination of microfluidics, microelectronics, and photonics enables highly sensitive molecular diagnostics for biomarker detection.
SPR (Surface Plasmon Resonance) chips can be used to detect various biomarkers, which help in the early diagnosis of cancer, neurogenerative diseases, etc.
SPR chips usually have gold on the glass. But their performance can be increased further by having nanostructured gold (nano-holes or nano-pillars). These can be fabricated using our nanofabrication services.
Flexible Sensors for health monitoring
The conventional photolithography and etching techniques allow the fabrication of sensors on flexible materials such PET, PI, PDMS, etc.,
We can provide large-size substrate fabrication services for manufacturing such sensors.
Point of Care Diagnosis
Lab on Chip (LOC)
A Lab-on-a-Chip (LOC) is a miniaturized device that integrates multiple laboratory functions onto a single chip. It enables rapid, cost-effective, and portable analysis by reducing reagent consumption and utilizing low-cost materials..
Genomics
DNA sequencing and extraction can be performed on chips fabricated using conventional semiconductor manufacturing technologies.
Ultrasonic Medical imaging
MEMS (microelectromechanical systems) advances allow low-cost, compact ultrasound sensors that make real-time 3D medical imaging possible.
The two leading technologies are capacitive micromachined ultrasonic transducers (CMUTs) and piezoelectric micro-machined ultrasonic transducers (PMUTs).
Apart from medical imaging, these can be used for Haptics, gesture recognition, etc.
We can provide MEMS fabrication services for these sensors.
MEMS-based Micropumps
For minute quantity fluid transportation
Applications in Microfluidic devices, Point of care for drug delivery, transdermal insulin delivery, blood transport, neurotransmitter delivery, etc.
Interested in our services or exploring collaboration opportunities? Get in touch with us to learn more about our cutting-edge biomedical solutions.