Lifesciences, Biomedical & Health Tech Solutions
At Nanosystems JP Inc., we leverage advanced silicon and semiconductor fabrication methods to create a diverse range of biochips and biomedical devices suitable for both in vivo and in vitro applications. We offer comprehensive bio-fabrication prototyping and manufacturing services, ensuring the delivery of high-quality, innovative solutions to meet the evolving needs of the biomedical sector.
Drug Discovery
Organ on Chip (OoCs)
OoCs simulate human organs on a microfluidic chip.
They help in drug discovery and testing on a chip.
Different chip platforms can simulate different organs such as the Brain (Brain on Chip), Lungs (Lungs on Chip), Liver, Kidney, heart, etc.
Micro-nanofabrication is the basis of fabricating such biochips.
MEA (Micro-Electrode Array)
MEA measures both extracellular and intracellular electrical activity. They can also provide stimulation for cell excitation. Microelectrode arrays can be used for drug development or food safety testing.
MEA can be in Vitro/ vivo.
The microneedle-based electrodes can be implanted in the brain (In Vivo), creating Brain-computer Interface (BCI)
We can also fabricate Polymer-based flexible electrocorticography (ECoG) electrode arrays.
Fabrication of both in vitro and in vivo MEA can be performed.
The General choice of material for in Vitro arrays is glass.
The micro-needles will be fabricated on Si using Deep etching or wet etching.
Cell sorters
Diaphoresis-based cell sorter can be fabricated on the glass using transparent electrodes like ITO.
Micro and nano sieves can be fabricated using Si tech to separate the cells.
Cell culture chips
Nano or micro-structured cell culture chips allows superior cell growth.
Customizable glass array (Blind Glass Via) for single-cell experiments.
Point of Care Diagnosis
Lab on Chip (LOC)
Lab on a chip is a miniature device that allows different functions, usually done separately in the lab, on a small chip.
It allows cheap, fast, portable analysis due to its small size, less requirement of reagents, and being from more inexpensive materials.
Biosensors for early disease diagnosis
Microfluidics with the combination of microelectronics and photonics, can be used for molecular diagnosis to detect different biomarkers.
SPR (Surface Plasmon Resonance) chips can be used to detect various biomarkers, which help in the early diagnosis of cancer, neurogenerative diseases, etc.
SPR chips usually have gold on the glass. But their performance can be increased further by having nanostructured gold (nano-holes or nano-pillars). These can be fabricated using our nanofabrication services.
Flexible Sensors for health monitoring
The conventional photolithography and etching techniques allow the fabrication of sensors on flexible materials such PET, PI, PDMS, etc.,
We can provide large-size substrate fabrication services for manufacturing such sensors.
Genomics
DNA sequencing, DNA extraction, etc., can be carried out on the chip fabricated using conventional Semiconductor fabrication technology.
Ultrasonic Medical imaging
MEMS (microelectromechanical systems) advances allow low-cost, compact ultrasound sensors that make real-time 3D medical imaging possible.
The two leading technologies are capacitive micromachined ultrasonic transducers (CMUTs) and piezoelectric micro-machined ultrasonic transducers (PMUTs).
Apart from medical imaging, these can be used for Haptics, gesture recognition, etc.
We can provide MEMS fabrication services for these sensors.
MEMS-based Micropumps
For minute quantity fluid transportation
Applications in Microfluidic devices, Point of care for drug delivery, transdermal insulin delivery, blood transport, neurotransmitter delivery, etc.
